Antibacterial Effects of Cork Fish Extract (Channa Striata) on Fusobacterium Nucleatum Bacteria as an Alternative Ingredient for the Medical of the Root Canal (In Vitro)
Introduction
Infection of the tooth root canal, often caused by gram-negative anaerobic bacteria such as fusobacterium nucleatum , is a common health problem. The treatment involves the use of medical ingredients for root canal to kill bacteria and other irritants in the root canal. Calcium hydroxide is the most commonly used material, but the ideal search for medical materials is still being carried out . This study investigated the potential of cork fish extract (channa striata ) as an alternative to the medical material of the root canal. The aim of this study is to determine the antibacterial effect of cork fish extract on fusobacterium nucleatum .
Background
Tooth root canal infection is a significant health problem worldwide. The infection is often caused by gram-negative anaerobic bacteria such as fusobacterium nucleatum . The treatment of root canal infection involves the use of medical ingredients to kill bacteria and other irritants in the root canal. Calcium hydroxide is the most commonly used material, but it has some limitations . It can cause irritation to the surrounding tissue and may not be effective against all types of bacteria. Therefore, there is a need to search for alternative medical materials that are effective and safe.
Research Methods
This study uses the posttest only control group design . Cork fish extract is obtained through the boiling process for 2 hours. The extract was diluted with DMSO to produce various concentrations (50%, 25%, 12.5%, 6.25%, and 3.125%). To determine the minimum inhibitory concentration value (KHM), the dilution method is used with liquid media BHIB. As for the minimum kill concentration (KBM), the drop plates miles Misra method is used with the media of Mueller Hinton Agar (MHA) .
Research Result
The results showed that cork fish extract had an antibacterial effect on fusobacterium nucleatum with a significance value p = 0,000 (p <0.05). KHM and KBM Cork fish extract against fusobacterium nucleatum obtained that is 12.5% and 25%.
Analysis and Conclusion
The results of this study indicate that cork fish extract has the potential as an alternative medical ingredient in root channels that are effective against fusobacterium nucleatum . The measured KHM and KBM indicate that cork fish extract can inhibit and kill these bacteria at certain concentrations. This study provides strong initial evidence that cork fish extract has the potential to be an effective alternative ingredient in the treatment of root canal infections .
The Importance of Further Research
Although this research shows promising results, further research is needed to confirm the effectiveness of cork fish extract in clinical applications. The research must include:
Toxicity Test: Long-term effect test: Formulation and Application:
Conclusion
This study provides strong initial evidence that cork fish extract has the potential to be an effective alternative ingredient in the treatment of root canal infections. Further research is needed to ensure its safety and effectiveness in clinical applications. The results of this study can contribute to the development of new medical materials for root canal treatment .
Future Directions
The results of this study can be used as a starting point for further research on the antibacterial effects of cork fish extract. Future studies can investigate the optimal formulation and application of cork fish extract as a medical material for root canal. Additionally, the long-term effects of cork fish extract on tooth tissue and its surroundings need to be further studied.
Limitations
This study has some limitations. The study was conducted in vitro, and the results may not be applicable to in vivo conditions. Additionally, the study only investigated the antibacterial effects of cork fish extract against fusobacterium nucleatum . Further studies are needed to investigate the effects of cork fish extract against other types of bacteria.
Conclusion
In conclusion, this study provides strong initial evidence that cork fish extract has the potential to be an effective alternative ingredient in the treatment of root canal infections. Further research is needed to ensure its safety and effectiveness in clinical applications. The results of this study can contribute to the development of new medical materials for root canal treatment .Q&A: Antibacterial Effects of Cork Fish Extract (Channa Striata) on Fusobacterium Nucleatum Bacteria as an Alternative Ingredient for the Medical of the Root Canal (In Vitro)
Frequently Asked Questions
Q: What is the purpose of this study?
A: The purpose of this study is to investigate the potential of cork fish extract (channa striata ) as an alternative to the medical material of the root canal, specifically against fusobacterium nucleatum bacteria.
Q: What is the significance of this study?
A: This study is significant because it provides initial evidence that cork fish extract has the potential to be an effective alternative ingredient in the treatment of root canal infections. The results of this study can contribute to the development of new medical materials for root canal treatment.
Q: What are the limitations of this study?
A: This study has some limitations. The study was conducted in vitro, and the results may not be applicable to in vivo conditions. Additionally, the study only investigated the antibacterial effects of cork fish extract against fusobacterium nucleatum . Further studies are needed to investigate the effects of cork fish extract against other types of bacteria.
Q: What are the potential applications of this study?
A: The results of this study can be used to develop new medical materials for root canal treatment. Additionally, the study can contribute to the development of new antibacterial agents for the treatment of various infections.
Q: What are the next steps for this research?
A: The next steps for this research include further studies to confirm the effectiveness of cork fish extract in clinical applications. This includes toxicity tests, long-term effect tests, and formulation and application studies.
Q: What are the potential benefits of using cork fish extract as a medical material?
A: The potential benefits of using cork fish extract as a medical material include its antibacterial effects, its potential to be a more effective alternative to calcium hydroxide, and its potential to be a more cost-effective option.
Q: What are the potential risks of using cork fish extract as a medical material?
A: The potential risks of using cork fish extract as a medical material include its potential toxicity to tooth tissue and its surroundings, its potential to cause allergic reactions, and its potential to interact with other medications.
Q: How can this research be applied to real-world scenarios?
A: This research can be applied to real-world scenarios by developing new medical materials for root canal treatment that are effective and safe. Additionally, the study can contribute to the development of new antibacterial agents for the treatment of various infections.
Conclusion
This Q&A article provides answers to frequently asked questions about the antibacterial effects of cork fish extract (channa striata ) on fusobacterium nucleatum bacteria as an alternative ingredient for the medical of the root canal (in vitro). The study provides initial evidence that cork fish extract has the potential to be an effective alternative ingredient in the treatment of root canal infections. Further research is needed to confirm the effectiveness of cork fish extract in clinical applications.