The Relationship Between Hemoglobin Levels and Thoracic Cardiac Ratio in Patients with Chronic Severe Anemia

Oct 13, 2025 by wbrum.org 1 views

The Relationship Between Hemoglobin Levels and Thoracic Cardiac Ratio in Patients with Chronic Severe Anemia

Chronic severe anemia is a condition characterized by hemoglobin levels below 7 g/dL for more than three months. This condition can lead to various complications, including heart enlargement and heart failure. In children, chronic severe anemia can have severe consequences on their health and development. Therefore, it is essential to understand the relationship between hemoglobin levels and thoracic cardiac ratio (RJT) in children with chronic severe anemia.

Chronic severe anemia is a common condition in children, particularly in developing countries. It is caused by a combination of genetic and environmental factors, including iron deficiency, malaria, and sickle cell disease. The condition can lead to various complications, including heart enlargement, heart failure, and increased risk of infections. In children, chronic severe anemia can affect their growth and development, leading to stunted growth, delayed cognitive development, and increased risk of mortality.

This cross-sectional research was conducted at Adam Malik Hajj Hospital in Medan in 2009, involving 30 children aged 1 to 15 years with chronic severe anemia. Hematological data were collected, and RJT was measured through a thoracic photo examination. The heart was considered enlarged if the RJT exceeded 50% (0.50). Univariate analysis and linear regression were used to analyze data.

The results showed that 90% (27 out of 30) children with severe anemia had a heart enlargement. Hemoglobin levels varied between 2.1 to 6.9 g/dL, with an average of 4.7 g/dL. Statistical analysis showed a significant relationship (p <0.05) and strong (r = -0.612) between hemoglobin and RJT levels. The lower the hemoglobin level, the greater the RJT value. Line equation Y = 0.66 - 0.03 (hemoglobin) can be used to predict RJT based on hemoglobin levels.

The findings of this study highlight the importance of early detection and treatment of chronic severe anemia in children. Low hemoglobin levels can be an indicator of RJT changes, which may indicate heart enlargement and increased risk of heart failure. The results of this study also emphasize the need for periodic RJT examination in children with chronic severe anemia to monitor the condition of the heart and prevent serious complications.

In conclusion, this study found a strong relationship between hemoglobin levels and thoracic cardiac ratio in children with chronic severe anemia. The findings of this study have significant implications for the management of chronic severe anemia in children. Early detection and treatment of the condition can prevent serious complications, including heart enlargement and heart failure. Further research with larger and multi-state samples is needed to strengthen this finding.

This study has several limitations, including a relatively small sample and focus on one hospital. Further research with larger and multi-state samples is needed to strengthen this finding. Additionally, this study only examined the relationship between hemoglobin levels and thoracic cardiac ratio in children with chronic severe anemia. Further research is needed to examine the relationship between hemoglobin levels and other cardiac parameters in children with chronic severe anemia.

Based on the findings of this study, the following recommendations are made:

Early detection and treatment of chronic severe anemia in children is essential to prevent serious complications, including heart enlargement and heart failure.
Periodic RJT examination in children with chronic severe anemia can help in monitoring the condition of the heart and prevent serious complications.
Further research with larger and multi-state samples is needed to strengthen the findings of this study.
The relationship between hemoglobin levels and other cardiac parameters in children with chronic severe anemia should be examined in further research.

This study highlights the importance of early detection and treatment of chronic severe anemia in children. Further research is needed to examine the relationship between hemoglobin levels and other cardiac parameters in children with chronic severe anemia. Additionally, further research is needed to examine the effectiveness of periodic RJT examination in preventing serious complications in children with chronic severe anemia.

A: Chronic severe anemia is a condition characterized by hemoglobin levels below 7 g/dL for more than three months. This condition can lead to various complications, including heart enlargement and heart failure.

A: The causes of chronic severe anemia include iron deficiency, malaria, sickle cell disease, and other genetic and environmental factors.

A: The thoracic cardiac ratio (RJT) is a measure of the size of the heart in relation to the chest cavity. It is measured through a thoracic photo examination and is considered enlarged if it exceeds 50% (0.50).

A: The results of this study showed a significant relationship (p <0.05) and strong (r = -0.612) between hemoglobin levels and RJT. The lower the hemoglobin level, the greater the RJT value.

A: The findings of this study highlight the importance of early detection and treatment of chronic severe anemia in children. Low hemoglobin levels can be an indicator of RJT changes, which may indicate heart enlargement and increased risk of heart failure.

A: This study has several limitations, including a relatively small sample and focus on one hospital. Further research with larger and multi-state samples is needed to strengthen this finding.

A: Based on the findings of this study, the following recommendations are made:

Early detection and treatment of chronic severe anemia in children is essential to prevent serious complications, including heart enlargement and heart failure.
Periodic RJT examination in children with chronic severe anemia can help in monitoring the condition of the heart and prevent serious complications.
Further research with larger and multi-state samples is needed to strengthen the findings of this study.
The relationship between hemoglobin levels and other cardiac parameters in children with chronic severe anemia should be examined in further research.

A: Further research is needed to examine the relationship between hemoglobin levels and other cardiac parameters in children with chronic severe anemia. Additionally, further research is needed to examine the effectiveness of periodic RJT examination in preventing serious complications in children with chronic severe anemia.

A: The findings of this study have significant implications for the management of chronic severe anemia in children. Early detection and treatment of the condition can prevent serious complications, including heart enlargement and heart failure. This research can also lead to the development of new diagnostic tools and treatments for chronic severe anemia.

A: The potential risks of this research include the use of invasive diagnostic procedures, such as thoracic photo examination, and the potential for adverse reactions to treatments. However, these risks can be minimized by using established diagnostic and treatment protocols and by conducting the research in a controlled and safe environment.