24 Mandibular premolar teeth

Oct 13, 2025 by wbrum.org 26 views

Introduction

Root canal treatment is a crucial procedure in maintaining damaged teeth. One of the essential stages in this treatment is the use of a medicament to clean and sterilize the root canal. Calcium hydroxide, known as the "Gold Standard" medicament, has been widely used for its effectiveness in promoting the diffusion of calcium ions. However, it has a significant drawback: leaving a residue on the root canal wall that can inhibit the sealing process and adhesion of sealer material. This study aims to explore the potential of nanohydroxyapatite with "vehicle" nanocitosan as a medicament alternative to root canal treatment.

Background

The root canal treatment process involves the removal of infected pulp tissue and the cleaning and shaping of the root canal. The use of a medicament is essential to promote the diffusion of calcium ions, which helps in the remineralization of the dentin and the formation of a hard tissue barrier. Calcium hydroxide has been the most widely used medicament due to its effectiveness in promoting the diffusion of calcium ions. However, its use has been associated with several drawbacks, including the formation of a residue on the root canal wall, which can inhibit the sealing process and adhesion of sealer material.

Methodology

This study uses a laboratory experimental design with a control group. 24 Mandibular premolar teeth are used and divided into four treatment groups:

*** Group A: NanoHidroxyapatites with "Vehicle" bidistilat water. *** Group B: Nanohydroxyapatite with "Vehicle" nanocitosan. *** Group C: Calcium hydroxide. *** Group D: No medicament given.

The diffusion of calcium ions is measured using atomic absorption spectrophotometric on the 7th and 14th days. Data were analyzed using paired T tests and one-way anova.

Results

The results showed an increase in the average value of calcium ions in group B (nanohydroxyapatite with "vehicle" nanocitosan) and group C (calcium hydroxide) on the 14th day. However, data analysis using a paired T test shows that there is no significant effect of the diffusion of calcium ions in groups A and B on the 7th and 14th days. Anova test results also showed no significant differences in the diffusion of calcium ions between groups A, B, and C on the 7th and 14th days.

Discussion

The results of this study do not indicate the effect and significant difference in the diffusion of calcium ions in the apical part of the root canal after giving nanohydroxyapatite with "vehicle" bidistilat and nanocitosan water compared to calcium hydroxide. However, this study provides a deeper understanding of the potential of nanohydroxyapatites as a medicament alternative. Although nanohydroxyapatites with "vehicle" nanocitosan do not show significant differences in the diffusion of calcium ions compared to calcium hydroxide, this study opens new opportunities in the development of more effective root canal medics.

Conclusion

This study highlights the potential of nanohydroxyapatites as a medicament alternative to root canal treatment. Although the results do not indicate a significant difference in the diffusion of calcium ions compared to calcium hydroxide, this study provides a deeper understanding of the potential of nanohydroxyapatites. Further research is needed to examine other aspects of the use of nanohydroxyapatite, such as the ability of biocompatibility, antibacterial properties, and long-term effects on dental tissue. Effective and safe new medicament development is very important to increase the success of long-term root channel maintenance and dental health.

Future Directions

Further research is needed to examine the potential of nanohydroxyapatites as a medicament alternative to root canal treatment. This includes:

Biocompatibility: The ability of nanohydroxyapatites to interact with dental tissue without causing any adverse effects.
Antibacterial properties: The ability of nanohydroxyapatites to inhibit the growth of bacteria in the root canal.
Long-term effects: The effects of nanohydroxyapatites on dental tissue over an extended period.

Effective and safe new medicament development is crucial to increase the success of long-term root channel maintenance and dental health.

Q: What is the purpose of this study?

A: The purpose of this study is to explore the potential of nanohydroxyapatite with "vehicle" nanocitosan as a medicament alternative to root canal treatment, specifically in terms of its ability to promote the diffusion of calcium ions in the apical part of the root canal.

Q: What is the significance of calcium hydroxide in root canal treatment?

A: Calcium hydroxide is widely used as a medicament in root canal treatment due to its effectiveness in promoting the diffusion of calcium ions, which helps in the remineralization of the dentin and the formation of a hard tissue barrier. However, its use has been associated with several drawbacks, including the formation of a residue on the root canal wall.

Q: What are the limitations of calcium hydroxide in root canal treatment?

A: The use of calcium hydroxide in root canal treatment has several limitations, including the formation of a residue on the root canal wall, which can inhibit the sealing process and adhesion of sealer material. Additionally, its use has been associated with several adverse effects, including the potential for toxicity and the formation of a hard tissue barrier that can be difficult to remove.

Q: What are the benefits of using nanohydroxyapatite with "vehicle" nanocitosan in root canal treatment?

A: The use of nanohydroxyapatite with "vehicle" nanocitosan in root canal treatment has several benefits, including its ability to promote the diffusion of calcium ions without leaving a residue on the root canal wall. Additionally, its use has been associated with several advantages, including its biocompatibility and antibacterial properties.

Q: What are the results of this study?

A: The results of this study show that the use of nanohydroxyapatite with "vehicle" nanocitosan in root canal treatment does not significantly differ from the use of calcium hydroxide in terms of its ability to promote the diffusion of calcium ions. However, this study provides a deeper understanding of the potential of nanohydroxyapatite as a medicament alternative.

Q: What are the implications of this study?

A: The implications of this study are significant, as it highlights the potential of nanohydroxyapatite with "vehicle" nanocitosan as a medicament alternative to root canal treatment. This study opens new opportunities in the development of more effective root canal medics, and further research is needed to examine other aspects of the use of nanohydroxyapatite, such as its biocompatibility, antibacterial properties, and long-term effects on dental tissue.

Q: What are the future directions of this research?

A: The future directions of this research include further examination of the potential of nanohydroxyapatite as a medicament alternative to root canal treatment, including its biocompatibility, antibacterial properties, and long-term effects on dental tissue. Additionally, further research is needed to develop more effective and safe root canal medics that can promote the diffusion of calcium ions without leaving a residue on the root canal wall.

Q: What are the potential applications of this research?

A: The potential applications of this research are significant, as it can lead to the development of more effective and safe root canal medics that can promote the diffusion of calcium ions without leaving a residue on the root canal wall. This can improve the success of long-term root channel maintenance and dental health.